Description

n-Acetyl-G-Carbethoxy Homotryptophan, Ethyl Ester is a specialized, high-purity synthetic amino acid derivative designed for advanced research and pharmaceutical development. This compound serves as a critical chiral building block and intermediate in the synthesis of complex peptides and bioactive molecules. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a building block for constructing complex molecular libraries in drug discovery programs targeting neurological and metabolic disorders.
• Peptide Synthesis: Serves as a protected tryptophan derivative in solid-phase and solution-phase peptide synthesis (SPPS) for producing custom peptides.
• Bioconjugation & Probe Development: Utilized in the development of fluorescent probes, affinity labels, and other bioconjugates due to its functionalized indole side chain.
• Academic & Industrial R&D: Employed in biochemical research to study enzyme mechanisms, protein-protein interactions, and structure-activity relationships (SAR).
• Process Chemistry: Acts as a standardized intermediate for scaling up the production of target molecules under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	n-Acetyl-G-Carbethoxy Homotryptophan, Ethyl Ester
CAS No.	351421-21-1
Molecular Formula	C19H24N2O5
Molecular Weight	360.41 g/mol
Synonyms	N-Acetyl-γ-carbethoxyhomo-L-tryptophan ethyl ester; Ethyl (2S)-2-acetamido-4-[(1H-indol-3-yl)methyl]-4-oxobutanoate; N-Acetyl-γ-(ethoxycarbonyl)-L-homotryptophan ethyl ester; Ac-γ-Carboethoxy-Hotrp-OEt; N-Acetyl-γ-carbethoxy-L-homotryptophan ethyl ester; Homo-L-tryptophan derivative, N-acetyl-γ-carbethoxy, ethyl ester; L-Tryptophan, N-acetyl-γ-(ethoxycarbonyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl-G-Carbethoxy Homotryptophan, Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.