Description

5-Chloro-2-Methyl-Nicotinic Acid Methyl Ester is a high-purity organic chemical building block, a key nicotinic acid derivative essential for advanced pharmaceutical synthesis and agrochemical research. Its primary value lies in its role as a versatile intermediate for constructing complex heterocyclic molecules with targeted biological activity. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, insecticides, and fungicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in medicinal chemistry and organic synthesis methodologies.
• Material Science Research: Investigated as a monomer or precursor for functional polymers and advanced organic materials.

Basic Information

Product Name	5-Chloro-2-Methyl-Nicotinic Acid Methyl Ester
CAS No.	350597-49-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Methyl 5-chloro-2-methylnicotinate; 5-Chloro-2-methyl-3-pyridinecarboxylic acid methyl ester; 3-Pyridinecarboxylic acid, 5-chloro-2-methyl-, methyl ester; 5-Chloro-2-methylnicotinic acid methyl ester; Methyl 5-chloro-2-methylpyridine-3-carboxylate; 5-Chloro-2-methyl-pyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methyl-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.