Description

trans-3-(4-Bromophenyl)Acrylic Acid tert-Butyl Ester CAS NO 350490-15-2 is a high-purity, versatile chemical intermediate characterized by its brominated aromatic and acrylic ester functional groups. This compound is of significant value in organic synthesis, serving as a key building block for constructing more complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its bromophenyl moiety.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating advanced organic electronic materials and liquid crystal displays (LCDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart specific properties like UV stability, flame retardancy, or altered refractive indices.
• Cross-Coupling Reactions (e.g., Suzuki, Heck): The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, a cornerstone of modern synthetic chemistry.
• Chemical Research & Development: Employed in academic and industrial labs for methodological studies and the exploration of new synthetic pathways.

Basic Information

Product Name	trans-3-(4-Bromophenyl)Acrylic Acid tert-Butyl Ester
CAS No.	350490-15-2
Molecular Formula	C₁₃H₁₅BrO₂
Molecular Weight	283.16 g/mol
Synonyms	(E)-3-(4-Bromophenyl)-2-propenoic acid 1,1-dimethylethyl ester; tert-Butyl (E)-3-(4-bromophenyl)acrylate; 4-Bromocinnamic acid tert-butyl ester; (E)-tert-Butyl 3-(4-bromophenyl)acrylate; trans-4-Bromocinnamic acid tert-butyl ester; (E)-3-(p-Bromophenyl)acrylic acid tert-butyl ester; p-Bromocinnamic acid t-butyl ester; t-Butyl trans-3-(4-bromophenyl)acrylate
EINECS	Contact for details

Quality Control

Our trans-3-(4-Bromophenyl)Acrylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to minimize risk of degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (trans-isomer)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.