Description

Diethyl (Boc-Aminomethyl)Phosphonate is a high-value, protected aminomethylphosphonate building block essential for modern synthetic organic and medicinal chemistry. Its primary value lies in enabling the efficient, stereoselective introduction of nitrogen-containing phosphonate groups, which are key precursors to α-aminophosphonic acids and their derivatives. This compound is critically needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel bioactive molecules and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of α-aminophosphonic acid analogs, which are potent enzyme inhibitors with therapeutic potential.
• Peptidomimetic Synthesis: Used in the preparation of phosphonate-based peptidomimetics, which mimic peptides but offer enhanced metabolic stability.
• Agrochemical Research: Serves as a precursor for novel herbicidal and plant growth regulatory compounds containing phosphonate moieties.
• Ligand and Catalyst Development: Employed in the creation of chiral phosphonate ligands for asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Utilized to develop activity-based probes and molecular tools for studying biological pathways.
• Material Science: A monomer or modifier for creating functional polymers with specific chelating or bioactive properties.

Basic Information

Product Name	Diethyl (Boc-Aminomethyl)Phosphonate
CAS No.	350027-05-3
Molecular Formula	C10H22NO5P
Molecular Weight	267.26 g/mol
Synonyms	Diethyl N-(tert-Butoxycarbonyl)aminomethylphosphonate; (Boc-Aminomethyl)phosphonic Acid Diethyl Ester; Diethyl [(tert-Butoxycarbonylamino)methyl]phosphonate; Diethyl P-[(N-Boc-amino)methyl]phosphonate; Boc-NH-CH2-P(O)(OEt)2; tert-Butyl N-[(diethoxyphosphoryl)methyl]carbamate; (N-Boc-Aminomethyl)phosphonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl (Boc-Aminomethyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.