Description

1-Methanesulfonyl-Piperidine-3-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine carboxylic acid ester core functionalized with a methanesulfonyl group. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecules with specific stereochemical and pharmacological properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting neurological and metabolic disorders.
• Chemical Synthesis Reagent: Used in medicinal chemistry for introducing the methanesulfonyl-piperidine moiety into lead compounds to modulate solubility, bioavailability, and receptor binding.
• Research & Development: Essential for academic and industrial R&D labs exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for complex organic molecules.

Basic Information

Product Name	1-Methanesulfonyl-Piperidine-3-Carboxylic Acid Ethyl Ester
CAS No.	349625-89-4
Molecular Formula	C10H19NO5S
Molecular Weight	265.33 g/mol
Synonyms	Ethyl 1-(methylsulfonyl)piperidine-3-carboxylate; Ethyl 1-(Methanesulfonyl)-3-piperidinecarboxylate; 3-Piperidinecarboxylic acid, 1-(methylsulfonyl)-, ethyl ester; 1-Methanesulfonylpiperidine-3-carboxylic Acid Ethyl Ester; 1-(Methylsulfonyl)piperidine-3-carboxylic Acid Ethyl Ester; 349625-89-4; Piperidine-3-carboxylic acid ethyl ester, 1-methanesulfonyl derivative
EINECS	Contact for details

Quality Control

Our 1-Methanesulfonyl-Piperidine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.