Description

Ethyl 1-(4-Methoxybenzoyl)-4-piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for R&D chemists and production teams in the global pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for innovative drug development and manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, particularly in neurological and psychiatric drug research.
• Chemical Synthesis Building Block: Used in multi-step organic synthesis to construct complex piperidine-based molecular frameworks.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for GMP and non-GMP scale-up production.
• Academic & Institutional Research: Utilized in university and institutional labs for pharmacological studies and novel compound library generation.
• Process Development: Serves as a standard in developing and optimizing robust, scalable synthetic routes for API manufacturing.

Basic Information

Product Name	Ethyl 1-(4-Methoxybenzoyl)-4-piperidinecarboxylate
CAS No.	349397-64-4
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	Ethyl 1-(4-Methoxybenzoyl)piperidine-4-carboxylate; 4-Piperidinecarboxylic acid, 1-(4-methoxybenzoyl)-, ethyl ester; 1-(4-Methoxybenzoyl)piperidine-4-carboxylic Acid Ethyl Ester; Ethyl 1-(p-Methoxybenzoyl)-4-piperidinecarboxylate; 349397-64-4; 1-(4-Methoxybenzoyl)-4-piperidinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-(4-Methoxybenzoyl)-4-piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.