Description

Ethyl n-[(2-Boc-Amino)Ethyl]Glycinate Hydrochloride is a protected amino acid derivative, specifically a glycine ester hydrochloride salt featuring a tert-butoxycarbonyl (Boc) protecting group on the amine. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering high purity and reliable reactivity for demanding pharmaceutical research. It is primarily needed by pharmaceutical R&D and fine chemical synthesis laboratories engaged in developing new therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the solid-phase and solution-phase synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected glycine derivative for the controlled elongation of peptide chains in research and development.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Proteomics Research: Employed in the synthesis of custom peptides for use as standards, probes, or inhibitors in biochemical assays.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic potential.
• Fine Chemical Synthesis: Acts as a versatile intermediate for the preparation of more complex, functionalized organic molecules.

Basic Information

Product Name	Ethyl n-[(2-Boc-Amino)Ethyl]Glycinate Hydrochloride
CAS No.	347890-34-0
Molecular Formula	C₁₂H₂₄N₂O₄·HCl
Molecular Weight	296.79 g/mol (Free base: 260.33)
Synonyms	Ethyl N-[(2-{[(tert-Butoxy)carbonyl]amino}ethyl)glycinate hydrochloride; Glycine, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-, ethyl ester, hydrochloride; Boc-NH-CH2-CH2-NH-CH2-COOEt·HCl; N-(2-Boc-aminoethyl)glycine ethyl ester hydrochloride; Ethyl 2-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]acetate hydrochloride; (2-{[(tert-Butoxycarbonyl)amino]ethyl}amino)acetic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl n-[(2-Boc-Amino)Ethyl]Glycinate Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.