Description

1-(4-Bromo-Phenyl)-Cyclopropanecarboxylic Acid tert-Butyl Ester is a high-purity organic building block featuring a cyclopropane ring and a brominated aromatic system. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the cyclopropane and bromophenyl motifs.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: The bromophenyl group makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	1-(4-Bromo-Phenyl)-Cyclopropanecarboxylic Acid tert-Butyl Ester
CAS No.	345965-53-9
Molecular Formula	C14H17BrO2
Molecular Weight	297.19 g/mol
Synonyms	tert-Butyl 1-(4-bromophenyl)cyclopropane-1-carboxylate; 1-(4-Bromophenyl)cyclopropanecarboxylic Acid 1,1-Dimethylethyl Ester; 1-(p-Bromophenyl)cyclopropanecarboxylic Acid tert-Butyl Ester; Cyclopropanecarboxylic Acid, 1-(4-Bromophenyl)-, 1,1-Dimethylethyl Ester; 345965-53-9; 1-(4-Bromophenyl)cyclopropanecarboxylic Acid t-Butyl Ester
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-Phenyl)-Cyclopropanecarboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.