Description

1'-Benzylspiro[Isochroman-1,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic compound class. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new therapeutic agents, especially within the central nervous system (CNS) and other targeted therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe: Serves as a core structure for developing tool compounds to study biological pathways and protein function.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against various biological targets.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial production.

Basic Information

Product Name	1'-Benzylspiro[Isochroman-1,4'-Piperidine]
CAS No.	345294-39-5
Molecular Formula	C23H27NO
Molecular Weight	333.47 g/mol
Synonyms	Spiro[isochroman-1,4'-piperidine], 1'-benzyl-; 1'-Benzylspiro[isochromane-1,4'-piperidine]; 1-Benzylspiro[isochroman-1,4'-piperidine]; 1'-Benzyl-1,4-dihydrospiro[isochromene-3,4'-piperidine]; Benzylspiroisochromanpiperidine; 345294-39-5; 1'-Benzylspiro[isochroman-1,4'-piperidine]
EINECS	Contact for details

Quality Control

Our 1'-Benzylspiro[Isochroman-1,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.