Description

Diethyl 5-Bromopyridin-2-Ylphosphonate is a high-value organophosphorus building block and reagent. This compound is essential for the synthesis of complex heterocyclic molecules, particularly in medicinal chemistry and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing pyridine-based scaffolds.

Application

• Pharmaceutical Intermediates: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate functionalized pyridine motifs.
• Material Science Precursors: Serves as a precursor for ligands and functional monomers used in catalysis and advanced polymer materials.
• Cross-Coupling Reactions: Acts as a phosphonate reagent in Horner-Wadsworth-Emmons (HWE) olefination reactions to form carbon-carbon double bonds.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	Diethyl 5-Bromopyridin-2-Ylphosphonate
CAS No.	344891-78-7
Molecular Formula	C9H13BrNO3P
Molecular Weight	294.08 g/mol
Synonyms	Diethyl (5-bromo-2-pyridinyl)phosphonate; 5-Bromo-2-pyridylphosphonic Acid Diethyl Ester; (5-Bromopyridin-2-yl)phosphonic Acid Diethyl Ester; Diethyl (5-Bromopyridin-2-yl)phosphonate; Phosphonic Acid, P-(5-Bromo-2-pyridinyl)-, Diethyl Ester; 344891-78-7; 5-Bromo-2-diethoxyphosphorylpyridine
EINECS	Contact for details

Quality Control

Our Diethyl 5-Bromopyridin-2-Ylphosphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.