Description

[1,4']Bipiperidinyl-4-Carboxylic Acid Ethyl Ester is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its versatile piperidine-based scaffold, which is crucial for the synthesis of complex molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel bioactive compounds.
• Organic Synthesis: Acts as a versatile precursor for constructing complex nitrogen-containing heterocycles and amide derivatives.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Academic & Industrial R&D: Utilized in exploratory research for developing new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	[1,4']Bipiperidinyl-4-Carboxylic Acid Ethyl Ester
CAS No.	344779-08-4
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	4-(4-Piperidinyl)-1-piperidinecarboxylic acid ethyl ester; Ethyl 4,4'-bipiperidine-1-carboxylate; 1,1'-(Ethoxycarbonyl)-4,4'-bipiperidine; 4-(Piperidin-4-yl)piperidine-1-carboxylic acid ethyl ester; UNII-6V8E3K8Q4F; 6V8E3K8Q4F; 1-Carbethoxy-4,4'-bipiperidine; 1,4'-Bipiperidine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our [1,4']Bipiperidinyl-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.