Description

Methyl 3-{[(4-Methylbenzene)Sulfonyl]Oxy}Cyclobutane-1-Carboxylate is a high-purity, synthetically valuable cyclobutane derivative functionalized with a tosylate leaving group and a methyl ester. This compound serves as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis, enabling the construction of complex, strained-ring molecular architectures. It is primarily utilized by research institutions and pharmaceutical R&D departments for the development of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing strained cyclobutane rings, which are increasingly explored for their unique biological activity.
• Organic Synthesis Building Block: The tosylate group facilitates nucleophilic substitution reactions, making it valuable for introducing the cyclobutane moiety into more complex molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs targeting various disease pathways.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides that leverage the physicochemical properties of the cyclobutane structure.
• Material Science Precursor: Potential starting material for synthesizing monomers or ligands used in advanced polymers and functional materials.

Basic Information

Product Name	Methyl 3-{[(4-Methylbenzene)Sulfonyl]Oxy}Cyclobutane-1-Carboxylate
CAS No.	344338-13-2
Molecular Formula	C14H18O5S
Molecular Weight	298.35 g/mol
Synonyms	Methyl 3-[(p-Toluenesulfonyl)oxy]cyclobutane-1-carboxylate; Methyl 3-(Tosyloxy)cyclobutane-1-carboxylate; 3-(p-Tolylsulfonyloxy)cyclobutanecarboxylic Acid Methyl Ester; 1-Carbomethoxy-3-(p-toluenesulfonyloxy)cyclobutane; Cyclobutanecarboxylic acid, 3-[(4-methylphenyl)sulfonyl]oxy]-, methyl ester; Methyl 3-(4-methylbenzenesulfonyloxy)cyclobutane-1-carboxylate; Tosyloxy Cyclobutane Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-{[(4-Methylbenzene)Sulfonyl]Oxy}Cyclobutane-1-Carboxylate adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical properties are provided and available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.