Description

Spiro[2.5]Oct-7-Ene-5-Carboxaldehyde, 4-Methyl- (9Ci) is a specialized spirocyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique strained ring system and reactive aldehyde functionality make it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those with spirocyclic or bridged ring systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique structure for bioactivity.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Organic Synthesis: A versatile reagent for cycloaddition reactions, nucleophilic additions, and reductive amination processes to create complex, three-dimensional molecules.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Fragrance and Flavor Chemistry: Potential use as an intermediate for synthesizing unique odorants and flavor compounds due to its constrained carboxaldehyde structure.

Basic Information

Product Name	Spiro[2.5]Oct-7-Ene-5-Carboxaldehyde, 4-Methyl- (9Ci)
CAS No.	344294-60-6
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	4-Methylspiro[2.5]oct-7-ene-5-carboxaldehyde; 4-Methylspiro[2.5]oct-7-ene-5-carbaldehyde; 4-Methyl-1-oxaspiro[2.5]oct-7-ene-5-carboxaldehyde; Spiro[2.5]oct-7-ene-5-carboxaldehyde, 4-methyl-; 344294-60-6; 4-Methylspiro(2.5)oct-7-ene-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Oct-7-Ene-5-Carboxaldehyde, 4-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.