Description

2-Amino-6-(tert-Butyl)-4-(2-Chlorophenyl)Nicotinonitrile is a high-value, multi-functional chemical intermediate characterized by its unique pyridine core structure. This compound matters for its critical role in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated aromatic and nitrile functionalities.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, ligands, and functional polymers.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological pathways and protein interactions.
• Catalyst Ligand Development: The amino and nitrile groups provide coordination sites for developing novel metal-organic catalysts.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Amino-6-(tert-Butyl)-4-(2-Chlorophenyl)Nicotinonitrile
CAS No.	344264-44-4
Molecular Formula	C16H16ClN3
Molecular Weight	285.77 g/mol
Synonyms	2-Amino-6-tert-butyl-4-(2-chlorophenyl)nicotinonitrile; 4-(2-Chlorophenyl)-2-amino-6-(tert-butyl)nicotinonitrile; 2-Amino-6-(1,1-dimethylethyl)-4-(2-chlorophenyl)-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 2-amino-6-(1,1-dimethylethyl)-4-(2-chlorophenyl)-; 2-Amino-6-tert-butyl-4-(o-chlorophenyl)nicotinonitrile; 2-Amino-4-(2-chlorophenyl)-6-(tert-butyl)pyridine-3-carbonitrile; 344264-44-4; 2-Amino-6-(tert-butyl)-4-(2-chlorophenyl)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(tert-Butyl)-4-(2-Chlorophenyl)Nicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.