Description

2-Amino-4-(2-Chlorophenyl)-6-(4-Chlorophenyl)-5-Methylnicotinonitrile is a high-value, multi-substituted pyridine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring dual chlorophenyl groups and a nitrile functionality, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides due to its bioactive pyridine core.
• Material Science: Building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile intermediate for constructing complex heterocycles like quinolines, acridines, and other fused ring systems in academic and industrial research.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.

Basic Information

Product Name	2-Amino-4-(2-Chlorophenyl)-6-(4-Chlorophenyl)-5-Methylnicotinonitrile
CAS No.	344264-24-0
Molecular Formula	C20H15Cl2N3
Molecular Weight	368.26 g/mol
Synonyms	5-Methyl-2-amino-4,6-bis(chlorophenyl)nicotinonitrile; 2-Amino-4,6-bis(chlorophenyl)-5-methyl-3-pyridinecarbonitrile; 4-(2-Chlorophenyl)-6-(4-chlorophenyl)-2-amino-5-methyl-3-cyanopyridine; 2-Amino-4-(2-chlorophenyl)-6-(4-chlorophenyl)-5-methyl-3-pyridinecarbonitrile; 3-Cyano-2-amino-4,6-di(chlorophenyl)-5-methylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(2-Chlorophenyl)-6-(4-Chlorophenyl)-5-Methylnicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports your R&D and scale-up processes with reliable, traceable material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if long-term storage is required to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.