Description

(Z)-3-(4-Chlorophenyl)-1-[3-(Trifluoromethyl)Phenyl]-2-Propen-1-One is a high-value, non-steroidal chalcone derivative characterized by its distinct molecular architecture. This compound serves as a critical advanced pharmaceutical intermediate and a versatile organic synthesis building block for research and development. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting inflammation, cancer, and metabolic disorders.
• Chemical Biology Probe: Used in research to study biological pathways and protein interactions due to its chalcone scaffold.
• Organic Light-Emitting Diode (OLED) Material Research: Investigated as an electron-transport or emissive layer component in optoelectronic devices.
• Agrochemical Intermediate: Serves as a building block for developing new active ingredients with herbicidal or fungicidal properties.
• Academic & Industrial R&D: Employed in methodological studies and the discovery of new chemical entities in medicinal and synthetic chemistry.
• Ligand in Catalysis: Potential use as a ligand or precursor for metal complexes in catalytic applications.

Basic Information

Product Name	(Z)-3-(4-Chlorophenyl)-1-[3-(Trifluoromethyl)Phenyl]-2-Propen-1-One
CAS No.	343374-73-2
Molecular Formula	C16H10ClF3O
Molecular Weight	310.70 g/mol
Synonyms	(Z)-3-(4-Chlorophenyl)-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one; (Z)-1-[3-(Trifluoromethyl)phenyl]-3-(4-chlorophenyl)-2-propen-1-one; 3-(4-Chlorophenyl)-1-[3-(trifluoromethyl)phenyl]-2-propen-1-one (Z-isomer); Chalcone derivative 343374-73-2; (Z)-3-(p-Chlorophenyl)-1-(m-trifluoromethylphenyl)propenone; (2Z)-3-(4-Chlorophenyl)-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our production of (Z)-3-(4-Chlorophenyl)-1-[3-(Trifluoromethyl)Phenyl]-2-Propen-1-One adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. All materials are fully characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.