Description

Azetidine-3-Carboxylic Acid Methyl Ester is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its constrained azetidine ring system, which is a key structural motif for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research chemists and process development teams in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the azetidine scaffold can impart unique biological activity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics & Bioisosteres: The ester functionality and ring strain make it a valuable component for creating conformationally restricted peptide analogs and bioisosteric replacements for proline or other amino acids.
• Material Science Precursor: Potential use in the synthesis of specialized polymers and functionalized surfaces with unique chemical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	Azetidine-3-Carboxylic Acid Methyl Ester
CAS No.	343238-58-4
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	Methyl Azetidine-3-carboxylate; 3-(Methoxycarbonyl)azetidine; Methyl 3-Azetidinecarboxylate; Azetidine-3-carboxylic Acid, Methyl Ester; 1-Azetidinecarboxylic Acid, Methyl Ester; 3-Carbomethoxyazetidine; Azetidine-3-methyl carboxylate
EINECS	Contact for details

Quality Control

Our Azetidine-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.