Description

Acetic Acid, Cyano[(3R)-3-Methylcyclopentylidene]-, Ethyl Ester, (2E)- (9Ci) is a specialized chiral intermediate featuring a cyanoacetate moiety integrated with a methylcyclopentylidene framework. This compound is valued for its role in asymmetric synthesis, serving as a key building block for constructing complex molecules with defined stereochemistry. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel therapeutic agents, particularly in constructing sterically defined carbon skeletons.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Agrochemical Synthesis: Employed in the production of advanced, stereospecific pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Fine Chemical Manufacturing: Serves as a high-value building block for creating specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new organic reactions and synthesizing complex natural product analogs.

Basic Information

Item	Details
Product Name	Acetic Acid, Cyano[(3R)-3-Methylcyclopentylidene]-, Ethyl Ester, (2E)- (9Ci)
CAS No.	342652-12-4
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(2E)-Ethyl 2-cyano-3-[(3R)-3-methylcyclopentylidene]propanoate; (E)-Ethyl 2-cyano-3-((R)-3-methylcyclopentylidene)propanoate; Ethyl (2E)-2-cyano-3-[(3R)-3-methylcyclopentylidene]prop-2-enoate; (E)-Ethyl 2-cyano-3-(3-methylcyclopentylidene)propanoate (mixed isomers); Cyano[(3R)-3-Methylcyclopentylidene]acetic Acid Ethyl Ester; (2E)-2-Cyano-3-[(3R)-3-methyl-1-cyclopenten-1-yl]-2-propenoic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chiral purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.