Description

Acetic Acid, Cyano[(3R)-3-Methylcyclopentylidene]-, Ethyl Ester, (2Z)- (9Ci) is a specialized chiral intermediate featuring a cyanoacetate moiety integrated into a methyl-substituted cyclopentylidene framework. This compound matters for its role as a high-value building block in the synthesis of complex, optically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing advanced active pharmaceutical ingredients (APIs), agrochemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of novel, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is critical for bioactivity.
• Fine Chemical Production: Serves as a precursor for creating complex esters, lactones, and other high-value specialty chemicals used in fragrances and advanced polymers.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Material Science: Potential use in the synthesis of monomers for specialty polymers with tailored optical or mechanical properties.

Basic Information

Product Name	Acetic Acid, Cyano[(3R)-3-Methylcyclopentylidene]-, Ethyl Ester, (2Z)- (9Ci)
CAS No.	342652-10-2
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	(2Z)-Ethyl 2-cyano-3-[(3R)-3-methylcyclopentylidene]propanoate; (Z)-Ethyl 2-cyano-3-((3R)-3-methylcyclopentylidene)propanoate; Ethyl (Z)-2-cyano-3-[(3R)-3-methylcyclopentylidene]propionate; 2-Propenoic acid, 2-cyano-3-[(3R)-3-methylcyclopentylidene]-, ethyl ester, (2Z)-; Cyano[(3R)-3-methylcyclopentylidene]acetic acid ethyl ester (Z)-isomer
EINECS	Contact for details

Quality Control

Our Acetic Acid, Cyano[(3R)-3-Methylcyclopentylidene]-, Ethyl Ester, (2Z)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.