Description

2-((3-Cyano-4-(3-Methoxyphenyl)-6-Oxo-1,4,5,6-Tetrahydropyridin-2-Yl)Thio)Acetamide is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 342594-57-4. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily targeted at research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for oncology, neurology, and anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of proprietary drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and scale-up development.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical assays due to its functionalized structure.

Basic Information

Product Name	2-((3-Cyano-4-(3-Methoxyphenyl)-6-Oxo-1,4,5,6-Tetrahydropyridin-2-Yl)Thio)Acetamide
CAS No.	342594-57-4
Molecular Formula	C15H13N3O2S
Molecular Weight	299.35 g/mol
Synonyms	2-[(3-Cyano-4-(3-methoxyphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl)thio]acetamide; 2-((3-Cyano-4-(3-methoxyphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl)thio)acetamide; 342594-57-4; 2-[(3-Cyano-4-(3-methoxyphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl)sulfanyl]acetamide; Acetamide, 2-((3-cyano-4-(3-methoxyphenyl)-6-oxo-1,4,5,6-tetrahydropyridin-2-yl)thio)-; 2-({3-Cyano-4-[3-(methoxy)phenyl]-6-oxo-1,4,5,6-tetrahydropyridin-2-yl}sulfanyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-((3-Cyano-4-(3-Methoxyphenyl)-6-Oxo-1,4,5,6-Tetrahydropyridin-2-Yl)Thio)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.