Description

Benzoyl Isocyanate, 4-Hydroxy- (9Ci) is a specialized aromatic isocyanate derivative, a key building block for synthesizing high-value heterocyclic compounds and functional polymers. Its reactive isocyanate and phenolic hydroxyl groups make it a versatile intermediate for creating tailored molecular architectures with specific properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and performance polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for creating urea and carbamate linkages in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its bifunctional reactivity.
• Polymer Modification: Acts as a cross-linking agent or chain extender in the production of specialty polyurethanes, polyureas, and other performance polymers with enhanced thermal or mechanical properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex heterocyclic scaffolds, such as benzoxazinones, which are prevalent in medicinal chemistry.
• Surface Coating Agents: Employed in the formulation of advanced adhesives, sealants, and coating materials where chemical resistance and durability are required.

Basic Information

Product Name	Benzoyl Isocyanate, 4-Hydroxy- (9Ci)
CAS No.	342403-13-8
Molecular Formula	C8H5NO3
Molecular Weight	163.13 g/mol
Synonyms	4-Hydroxybenzoyl isocyanate; p-Hydroxybenzoyl isocyanate; 4-Hydroxybenzoic acid isocyanate; Isocyanic acid 4-hydroxybenzoyl ester; Benzoyl isocyanate, 4-hydroxy-; 4-Carboxyphenyl isocyanate (tautomeric form); (4-Hydroxyphenyl)carbonyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of Benzoyl Isocyanate, 4-Hydroxy- (9Ci) is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D and scale-up processes. Our quality systems are designed to support development work under cGMP and ISO guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.