Description

(5Z)-2-Amino-5-(4-Chlorobenzylidene)-4,6-Dimethyl-5H-Cyclopenta[B]Pyridine-3,7-Dicarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting various therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and protein interactions.
• Organic Synthesis: A versatile intermediate for constructing complex polycyclic nitrogen-containing heterocycles.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodology development.
• Preclinical Development: Employed in the production of compounds for early-stage pharmacological and toxicological evaluation.

Basic Information

Product Name	(5Z)-2-Amino-5-(4-Chlorobenzylidene)-4,6-Dimethyl-5H-Cyclopenta[B]Pyridine-3,7-Dicarbonitrile
CAS No.	340226-23-5
Molecular Formula	C19H13ClN4
Molecular Weight	332.79 g/mol
Synonyms	2-Amino-5-[(Z)-(4-chlorophenyl)methylene]-4,6-dimethyl-5H-cyclopenta[b]pyridine-3,7-dicarbonitrile; 5-[(Z)-(4-Chlorophenyl)methylene]-2-amino-4,6-dimethyl-5H-cyclopenta[b]pyridine-3,7-dicarbonitrile; (5Z)-2-Amino-5-(4-chlorobenzylidene)-4,6-dimethyl-5H-cyclopenta[b]pyridine-3,7-dicarbonitrile; 5-(4-Chlorobenzylidene)-2-amino-4,6-dimethyl-5H-cyclopenta[b]pyridine-3,7-dicarbonitrile; CAS 340226-23-5
EINECS	Contact for details

Quality Control

Our (5Z)-2-Amino-5-(4-Chlorobenzylidene)-4,6-Dimethyl-5H-Cyclopenta[B]Pyridine-3,7-Dicarbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.