Description

Tucotuzumab Celmoleukin is a recombinant fusion protein designed for targeted immunotherapy. This compound is of significant interest for its potential to modulate specific immune pathways in a controlled manner. It is primarily utilized by pharmaceutical R&D teams and biopharmaceutical manufacturers engaged in the development of novel oncology and immunology therapeutics.

Application

• Oncology Research: Investigation as a potential therapeutic agent for various cancer types in preclinical and clinical studies.
• Immunotherapy Development: Serves as a key component in the research and formulation of advanced cell-based and biologic cancer treatments.
• Targeted Drug Conjugates: Potential use as a targeting moiety in antibody-drug conjugate (ADC) platforms for precise drug delivery.
• Biopharmaceutical Manufacturing: Used as a critical raw material or intermediate in the GMP production of biologic drug substances.
• Mechanistic Studies: Tool for studying specific cytokine-receptor interactions and immune cell activation pathways in vitro.
• Assay Development: Employed as a standard or reference material in the development of bioanalytical assays (e.g., ELISA, cell-based potency assays).

Basic Information

Product Name	Tucotuzumab Celmoleukin
CAS No.	339986-90-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	EMD 273066; huKS-IL2 Immunocytokine; KS-IL2; Tucotuzumab; Celmoleukin; Anti-human EpCAM Recombinant Immunocytokine; huKS-IL2 Fusion Protein; Recombinant Anti-EPCAM Fused with Interleukin-2
EINECS	Contact for details

Quality Control

Our Tucotuzumab Celmoleukin is produced and controlled under a stringent quality management system. Each batch is subjected to a comprehensive battery of analytical tests to ensure identity, purity, potency, and safety, meeting the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, biological activity, endotoxin levels, and sterility (where applicable) are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, store at 2-8°C. This hygroscopic (moisture-sensitive) material should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation. Aliquot into single-use vials to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (SDS-PAGE / Mass Spec)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 95.0%
Protein Content (UV-A280)	Contact for details
Biological Activity (Cell-based Assay)	Contact for details
Endotoxin (LAL)	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile (for aseptically filled vials)
Residual Moisture (KF)	< 3.0% (for lyophilized form)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.