Description

6-(4-Nitrophenyl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic pyridopyrimidine core. This compound matters for its role as a critical building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. Pharmaceutical R&D teams and fine chemical manufacturers need this material for synthesizing potential drug candidates targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex small-molecule drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a scaffold for structure-activity relationship (SAR) studies in medicinal chemistry.
• Chemical Synthesis: Serves as a versatile building block for constructing more complex polyheterocyclic systems in organic chemistry.
• Academic & Contract Research: Employed in university and CRO laboratories for investigating new chemical entities and biological mechanisms.
• Process Development: Utilized in scaling up synthetic routes from milligram to kilogram scale for pre-clinical and clinical trial material supply.

Basic Information

Product Name	6-(4-Nitrophenyl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-2-Amine
CAS No.	338791-45-0
Molecular Formula	C15H15N5O2
Molecular Weight	297.31 g/mol
Synonyms	6-(4-Nitrophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine; 2-Amino-6-(4-nitrophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 338791-45-0; 6-(p-Nitrophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine; Pyrido[4,3-d]pyrimidin-2-amine, 6-(4-nitrophenyl)-5,6,7,8-tetrahydro-; 6-(4-Nitrophenyl)-5,6,7,8-tetrahydro-2-pyrido[4,3-d]pyrimidinamine
EINECS	Contact for details

Quality Control

Our 6-(4-Nitrophenyl)-5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.