Description

6-Oxo-1-(4-(Trifluoromethyl)Benzyl)-1,6-Dihydropyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridinecarboxylic acid core and trifluoromethylbenzyl substituent. This compound matters as a critical building block for medicinal chemistry research and development, offering a versatile scaffold for creating novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing targeted molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, oncology, and central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization due to its modifiable carboxylic acid and ketone functional groups.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides, leveraging the biological activity of the pyridine and trifluoromethyl motifs.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and biological pathways in academic and industrial research settings.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex, high-value organic molecules in custom synthesis and contract manufacturing.

Basic Information

Product Name	6-Oxo-1-(4-(Trifluoromethyl)Benzyl)-1,6-Dihydropyridine-3-Carboxylic Acid
CAS No.	338783-75-8
Molecular Formula	C14H10F3NO3
Molecular Weight	297.23 g/mol
Synonyms	1-(4-(Trifluoromethyl)benzyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid; 1-[(4-Trifluoromethyl)benzyl]-6-oxo-1,6-dihydro-3-pyridinecarboxylic Acid; 3-Pyridinecarboxylic acid, 1,6-dihydro-1-[[4-(trifluoromethyl)phenyl]methyl]-6-oxo-; 338783-75-8; 6-Oxo-1-[(4-trifluoromethylphenyl)methyl]-1,6-dihydropyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Oxo-1-(4-(Trifluoromethyl)Benzyl)-1,6-Dihydropyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize shelf life.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.