Description

3-[(4-Methylpiperazino)Carbonyl]-1-[4-(Trifluoromethyl)Benzyl]-2(1H)-Pyridinone is a high-value, non-nucleoside pharmaceutical intermediate with a distinct trifluoromethylbenzyl and methylpiperazine carboxamide structure. This compound is critical for research and development in medicinal chemistry, particularly for targeting specific enzyme pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or inhibitor in enzymatic assays and pharmacological profiling.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the trifluoromethylbenzyl and piperazine carbonyl motifs into complex molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	3-[(4-Methylpiperazino)Carbonyl]-1-[4-(Trifluoromethyl)Benzyl]-2(1H)-Pyridinone
CAS No.	338782-11-9
Molecular Formula	C19H20F3N3O2
Molecular Weight	379.38 g/mol
Synonyms	1-[4-(Trifluoromethyl)benzyl]-3-[(4-methylpiperazin-1-yl)carbonyl]pyridin-2(1H)-one; 3-[(4-Methyl-1-piperazinyl)carbonyl]-1-[[4-(trifluoromethyl)phenyl]methyl]-2(1H)-pyridinone; 1-[(4-Trifluoromethyl)benzyl]-3-(4-methylpiperazine-1-carbonyl)pyridin-2(1H)-one; CAS 338782-11-9
EINECS	Contact for details

Quality Control

Every batch of 3-[(4-Methylpiperazino)Carbonyl]-1-[4-(Trifluoromethyl)Benzyl]-2(1H)-Pyridinone is manufactured under strict quality management systems. We provide comprehensive analytical data to support research and regulatory filings, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by HPLC. Certificates of Analysis (COA) detailing batch-specific results are available for all shipments, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.