Description

1-[3,5-Bis(Trifluoromethyl)Benzyl]-n-Methyl-2-Oxo-1,2-Dihydro-3-Pyridinecarboxamide is a high-value, specialized organic intermediate featuring a pyridone core flanked by trifluoromethylbenzyl and methylcarboxamide groups. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique fluorine-containing structure imparts desirable metabolic stability and lipophilicity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated molecules for enhanced bioavailability and target binding.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl groups contribute to improved environmental stability and efficacy.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Advanced Material Precursor: Potential use in the synthesis of specialty polymers or liquid crystals that benefit from fluorine's unique electronic properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Reference Standard: Provided as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	1-[3,5-Bis(Trifluoromethyl)Benzyl]-n-Methyl-2-Oxo-1,2-Dihydro-3-Pyridinecarboxamide
CAS No.	338782-03-9
Molecular Formula	C17H12F6N2O2
Molecular Weight	390.28 g/mol
Synonyms	N-Methyl-1-[3,5-bis(trifluoromethyl)benzyl]-2-oxo-1,2-dihydropyridine-3-carboxamide; 1-[(3,5-Bis(trifluoromethyl)phenyl)methyl]-N-methyl-2-oxo-1,2-dihydro-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 1-[3,5-bis(trifluoromethyl)benzyl]-N-methyl-1,2-dihydro-2-oxo-; 338782-03-9; 1-(3,5-Bis(trifluoromethyl)benzyl)-N-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
EINECS	Contact for details

Quality Control

Our 1-[3,5-Bis(Trifluoromethyl)Benzyl]-n-Methyl-2-Oxo-1,2-Dihydro-3-Pyridinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with relevant research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.