Description

3-(Prop-2-En-1-Yl)-2-(Propylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is a sophisticated spirocyclic quinazolinone derivative, a high-value synthetic intermediate prized for its complex molecular architecture. This compound matters for its role in advanced pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules targeting specific enzymatic pathways. Industrial chemists and R&D laboratories in the pharmaceutical, agrochemical, and fine chemical sectors require this precise building block to drive innovation in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those with spirocyclic or quinazolinone cores for oncology and CNS research.
• Agrochemical Research: Used in developing novel active ingredients for crop protection with potential herbicidal or fungicidal properties.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study protein-ligand interactions and enzyme inhibition.
• Material Science: Exploration of advanced organic electronic materials or liquid crystals due to its rigid, fused polycyclic structure.
• Academic & Contract Research: Fundamental research in organic methodology and heterocyclic chemistry within university and CRO laboratories.
• Custom Synthesis: A starting material for bespoke chemical synthesis services targeting specialized client projects.

Basic Information

Product Name	3-(Prop-2-En-1-Yl)-2-(Propylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One
CAS No.	337496-43-2
Molecular Formula	C22H26N2OS
Molecular Weight	366.52 g/mol
Synonyms	2-(Propylthio)-3-(2-propen-1-yl)-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; 3-Allyl-2-propylsulfanyl-3H-spiro[1,3-benzodiazine-5,1'-cyclopentane]-4-one; Spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one, 3-(2-propen-1-yl)-2-(propylthio)-; CAS 337496-43-2; 3-Allyl-2-(propylthio)spiro[cyclopentane-1,5'-benzo[h]quinazolin]-4'(6'H)-one
EINECS	Contact for details

Quality Control

Our production of 3-(Prop-2-En-1-Yl)-2-(Propylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization including HPLC, NMR, and MS to confirm identity and high purity levels, typically ≥95% to ≥98% (by HPLC). Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0% (Typical: ≥97.0%)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.