Description

4-Ethyl-5-Oxo-4,5,6,7-Tetrahydrospiro(Benzo[H][1,2,4]Triazolo[4,3-A]Quinazoline-6,1'-Cyclohexane) is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its intricate fused-ring spiro structure makes it a valuable scaffold for developing novel pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as an intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Employed in universities and research institutes for studying novel heterocyclic reactions and the properties of complex spiro-fused ring systems.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	4-Ethyl-5-Oxo-4,5,6,7-Tetrahydrospiro(Benzo[H][1,2,4]Triazolo[4,3-A]Quinazoline-6,1'-Cyclohexane)
CAS No.	337487-99-7
Molecular Formula	C20H24N4O
Molecular Weight	336.44 g/mol
Synonyms	4-Ethyl-5-oxo-4,5,6,7-tetrahydrospiro[benzo[h][1,2,4]triazolo[4,3-a]quinazoline-6,1'-cyclohexane]; Spiro[cyclohexane-1,6'-[6,7]dihydrobenzo[h][1,2,4]triazolo[4,3-a]quinazolin]-5'(4'H)-one, 4'-Ethyl-; 4'-Ethyl-4',5',6',7'-tetrahydrospiro[cyclohexane-1,6'-benzo[h][1,2,4]triazolo[4,3-a]quinazolin]-5'(1'H)-one; CAS 337487-99-7
EINECS	Contact for details

Quality Control

Our 4-Ethyl-5-Oxo-4,5,6,7-Tetrahydrospiro(Benzo[H][1,2,4]Triazolo[4,3-A]Quinazoline-6,1'-Cyclohexane) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.