Description

2-Amino-4-(2-Chlorophenyl)-6-Isobutylnicotinonitrile is a specialized organic intermediate featuring a nicotinonitrile core substituted with amino, chlorophenyl, and isobutyl groups. This compound matters for its role as a critical building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or building block for advanced polymers and organic electronic materials due to its conjugated system.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies in cross-coupling, cyclization, and other complex organic transformations.
• Ligand & Catalyst Development: The amino and nitrile functionalities make it a useful scaffold for designing novel ligands for metal catalysis.

Basic Information

Product Name	2-Amino-4-(2-Chlorophenyl)-6-Isobutylnicotinonitrile
CAS No.	337474-61-0
Molecular Formula	C16H16ClN3
Molecular Weight	285.77 g/mol
Synonyms	6-Isobutyl-2-amino-4-(2-chlorophenyl)nicotinonitrile; 4-(2-Chlorophenyl)-2-amino-6-isobutyl-3-pyridinecarbonitrile; 2-Amino-4-(2-chlorophenyl)-6-(2-methylpropyl)nicotinonitrile; 3-Pyridinecarbonitrile, 2-amino-4-(2-chlorophenyl)-6-(2-methylpropyl)-; 2-Amino-4-(o-chlorophenyl)-6-isobutylnicotinonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(2-Chlorophenyl)-6-Isobutylnicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.