Description

4-Amino-2,6-Dichloro-Benzoic Acid tert-Butyl Ester is a high-purity, protected benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of an amino group and halogen substituents on an aromatic ring, protected by a tert-butyl ester, which provides excellent stability and reactivity control. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antibiotic and anti-inflammatory drug research.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science Precursor: Intermediate in the synthesis of advanced polymers and liquid crystals with specific optical or electronic properties.
• Organic Synthesis Research: Versatile starting material for academic and industrial R&D exploring new heterocyclic compounds and complex molecular architectures.
• Peptide Mimetics: Utilized in the design and synthesis of non-natural amino acids and peptide analogs for biomedical applications.

Basic Information

Product Name	4-Amino-2,6-Dichloro-Benzoic Acid tert-Butyl Ester
CAS No.	336818-35-0
Molecular Formula	C11H13Cl2NO2
Molecular Weight	262.13 g/mol
Synonyms	tert-Butyl 4-Amino-2,6-dichlorobenzoate; 2,6-Dichloro-4-aminobenzoic Acid tert-Butyl Ester; Benzoic acid, 4-amino-2,6-dichloro-, 1,1-dimethylethyl ester; 4-Amino-2,6-dichlorobenzoic acid 1,1-dimethylethyl ester; t-Butyl 4-amino-2,6-dichlorobenzoate; 336818-35-0; 4-Amino-2,6-dichloro-benzoic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-Amino-2,6-Dichloro-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, and NMR for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.