Description

Neurodye Rh-795 is a high-purity, membrane-potential sensitive fluorescent dye widely used in neuroscience and cellular biophysics research. Its core value lies in its ability to provide stable, long-term monitoring of neuronal activity and membrane potential changes with minimal photobleaching and cytotoxicity. This product is essential for researchers and manufacturers in the fields of neurobiology, electrophysiology, and high-throughput screening for drug discovery. The pure grade ensures consistent, reliable performance in sensitive imaging and diagnostic applications.

Application

• Neuronal Activity Imaging: Long-term staining and monitoring of membrane potential in live neurons and brain slices.
• Cardiac Electrophysiology: Optical mapping of action potentials in cardiac myocytes and tissue.
• High-Content Screening (HCS): As a key reagent in cell-based assays for neurological drug discovery and toxicity testing.
• In Vitro Diagnostics (IVD) Development: Component in assay kits for studying ion channel function and cellular excitability.
• Cellular Biophysics Research: Investigation of mitochondrial membrane potential and other bioenergetic parameters.
• Fluorescent Probe Synthesis: Serving as a precursor or core structure for developing next-generation voltage-sensitive dyes.

Basic Information

Product Name	Neurodye Rh-795, Pure
CAS No.	336185-18-3
Molecular Formula	C29H31ClN2O3
Molecular Weight	491.02 g/mol
Synonyms	RH-795; RH795; Neuro-Dye RH-795; Rhodamine 795; N-(4-(Dibutylamino)phenyl)methylidene]-2,3,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-9-ylidene]ammonium chloride; Voltage-sensitive dye RH-795; Potentiometric dye RH-795; 4-[[(2,3,6,7-Tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-yl)methylene]amino]-N,N-dibutylbenzenaminium chloride
EINECS	Contact for details

Quality Control

Our Neurodye Rh-795 is manufactured under strict quality management systems to ensure the highest standards of purity and batch-to-batch consistency for research and diagnostic use. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectral analysis (UV-Vis, Fluorescence), and identity confirmation (NMR, MS). Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccation and under an inert atmosphere to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	Dark green to purple crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	λmax conforms (Typically ~530 nm in methanol)
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Fluorescence Properties	Ex/Em conforms to reference (Typically ~530/712 nm)
Solubility	Soluble in DMSO, DMF, methanol; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.