Description

(E)-(4-(2-(Benzyloxy)-4-Fluorophenyl)-2,6-Diisopropyl-5-(Prop-1-Enyl)Pyridin-3-Yl)Methanol is a high-purity, advanced pharmaceutical intermediate characterized by its complex pyridine-based structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. Pharmaceutical R&D and manufacturing organizations need this precise chemical to enable the development and scalable production of next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic areas.
• Organic Synthesis Building Block: Utilized in research and development for constructing novel heterocyclic compounds, leveraging its reactive methanol and prop-1-enyl functional groups for further chemical transformations.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential biological activity.
• Process Chemistry & Scale-Up: Used in pilot plant and commercial-scale manufacturing processes to ensure consistent, high-yield production of target APIs under current Good Manufacturing Practices (cGMP).
• Contract Research & Manufacturing (CRAM): Supplied to service organizations specializing in custom synthesis and development for the global pharmaceutical industry.

Basic Information

Product Name	(E)-(4-(2-(Benzyloxy)-4-Fluorophenyl)-2,6-Diisopropyl-5-(Prop-1-Enyl)Pyridin-3-Yl)Methanol
CAS No.	334933-65-2
Molecular Formula	C29H32FNO2
Molecular Weight	445.57 g/mol
Synonyms	(E)-[4-(2-Benzyloxy-4-fluorophenyl)-2,6-diisopropyl-5-(prop-1-en-1-yl)pyridin-3-yl]methanol; 3-Pyridinemethanol, 4-[2-(benzyloxy)-4-fluorophenyl]-5-(1E)-1-propen-1-yl-2,6-bis(1-methylethyl)-, (E)-; 334933-65-2; 4-[2-(Benzyloxy)-4-fluorophenyl]-5-[(1E)-1-propen-1-yl]-2,6-bis(1-methylethyl)-3-pyridinemethanol
EINECS	Contact for details

Quality Control

Our (E)-(4-(2-(Benzyloxy)-4-Fluorophenyl)-2,6-Diisopropyl-5-(Prop-1-Enyl)Pyridin-3-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with stringent specifications for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.