Description

3-Bromo-2-Fluorobenzoic Acid Ethyl Ester is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound serves as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce halogenated fluorobenzoate motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Material Science: Serves as a building block for creating specialized ligands for catalysis and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for method development and exploring new chemical spaces in medicinal chemistry.
• Fluorine Chemistry: A valuable substrate for further functionalization via cross-coupling reactions, nucleophilic substitutions, and hydrolysis to access other fluorinated derivatives.

Basic Information

Product Name	3-Bromo-2-Fluorobenzoic Acid Ethyl Ester
CAS No.	334792-76-6
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	Ethyl 3-Bromo-2-fluorobenzoate; 2-Fluoro-3-bromobenzoic Acid Ethyl Ester; Benzoic acid, 3-bromo-2-fluoro-, ethyl ester; 3-Bromo-2-fluorobenzoic acid ethyl ester; Ethyl 3-bromo-2-fluorobenzoate; 334792-76-6; 3-Bromo-2-fluoro-benzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluorobenzoic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. The compound is moisture-sensitive; ensure containers are sealed to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.