Description

[(4-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound matters because it serves as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators requiring specific sulfonamide and aryl bromide functionalities.
• Peptidomimetic Synthesis: Serves as a precursor for non-peptide scaffolds that mimic peptide structure and function, useful in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig amination.
• Material Science Precursor: Can be utilized in the synthesis of monomers or functional agents for advanced polymers and specialty materials.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	[(4-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester
CAS No.	333451-79-9
Molecular Formula	C16H16BrNO4S
Molecular Weight	398.27 g/mol
Synonyms	Methyl [(4-bromophenyl)(4-tolylsulfonyl)amino]acetate; Methyl 2-[(4-bromophenyl)(4-methylphenyl)sulfonylamino]acetate; N-[(4-Bromophenyl)(4-methylphenyl)sulfonyl]glycine methyl ester; Methyl N-[(4-bromophenyl)-p-toluenesulfonamido]acetate; Methyl {[(4-bromophenyl)(4-methylphenyl)sulfonyl]amino}acetate; p-Toluenesulfonamide, N-[(4-bromophenyl)carbonyl]-, methyl ester; 333451-79-9
EINECS	Contact for details

Quality Control

Our [(4-Bromo-Phenyl)-(Toluene-4-Sulfonyl)-Amino]-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.