Description

n-(1,1-Dimethylethyl)-3-Iodo-4-Pyridinecarboxamide is a high-value, halogenated pyridine derivative used as a key synthetic intermediate in advanced organic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex chemical synthesis. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials, serving the needs of the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic materials and polymers with specific electronic or photophysical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Item	Details
Product Name	n-(1,1-Dimethylethyl)-3-Iodo-4-Pyridinecarboxamide
CAS No.	331969-21-2
Molecular Formula	C10H13IN2O
Molecular Weight	304.13 g/mol
Synonyms	tert-Butyl 3-iodopyridine-4-carboxamide; 3-Iodo-N-(tert-butyl)isonicotinamide; 4-Pyridinecarboxamide, N-(1,1-dimethylethyl)-3-iodo-; N-tert-Butyl-3-iodoisonicotinamide; 3-Iodo-N-tert-butylisonicotinamide; 3-Iodo-4-carbamoylpyridine, N-tert-butyl derivative; TBIPA (abbreviation)
EINECS	Contact for details

Quality Control

Our n-(1,1-Dimethylethyl)-3-Iodo-4-Pyridinecarboxamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.