Description

[2-(Bromomethyl)-2-(2,4-Dichlorophenyl)-1,3-Dioxolan-4-Yl]Methyl Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its unique dioxolane ring structure functionalized with bromomethyl and benzoate groups. This compound matters for its critical role as a key synthetic building block in the development of complex active pharmaceutical ingredients (APIs), particularly in antifungal and other therapeutic classes. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to ensure the efficiency and scalability of their synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex antifungal agents and other specialized active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Utilized in research and development for constructing complex molecular architectures, leveraging its reactive bromomethyl and ester functionalities.
• Agrochemical Research: Serves as a key intermediate in the development of novel crop protection agents and pesticides, where the dichlorophenyl moiety is often significant for bioactivity.
• Chemical Biology & Medicinal Chemistry: Used in the design and synthesis of probe molecules and candidate compounds for target identification and drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific molecules under cGMP conditions.

Basic Information

Product Name	[2-(Bromomethyl)-2-(2,4-Dichlorophenyl)-1,3-Dioxolan-4-Yl]Methyl Benzoate
CAS No.	331949-30-5
Molecular Formula	C18H15BrCl2O4
Molecular Weight	446.12 g/mol
Synonyms	Benzoic acid, [2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl ester; 4-(Bromomethyl)-4-(2,4-dichlorophenyl)-2-oxo-1,3-dioxolane-5-methyl benzoate; (4R/S)-[2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl benzoate; 2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanol benzoate ester; Dioxolane benzoate intermediate 331949-30-5
EINECS	Contact for details

Quality Control

Our [2-(Bromomethyl)-2-(2,4-Dichlorophenyl)-1,3-Dioxolan-4-Yl]Methyl Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided for every shipment, and we can support development with analytical method transfer and validation data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture uptake. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.