Description

2-Methyl-4-((Trimethylsilyl)Ethynyl)Thiazole CAS NO 329203-85-2 is a specialized organosilicon-thiazole hybrid compound featuring a reactive ethynyl group protected by a trimethylsilyl moiety. This unique structure makes it a valuable advanced intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the thiazole ring's bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Ligand Synthesis: Utilized for creating novel ligands in catalysis and coordination chemistry due to the nitrogen and sulfur donor atoms.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes and tags for studying biological systems.
• Academic & Industrial R&D: Fundamental research compound for exploring new synthetic methodologies and reaction pathways involving protected alkynes.

Basic Information

Product Name	2-Methyl-4-((Trimethylsilyl)Ethynyl)Thiazole
CAS No.	329203-85-2
Molecular Formula	C9H15NSSi
Molecular Weight	197.38 g/mol
Synonyms	4-((Trimethylsilyl)ethynyl)-2-methylthiazole; 2-Methyl-4-[(trimethylsilyl)ethynyl]thiazole; 2-Methyl-4-(trimethylsilylethynyl)thiazole; Thiazole, 2-methyl-4-[(trimethylsilyl)ethynyl]-; TMS-Ethynyl Thiazole Derivative
EINECS	Contact for details

Quality Control

Our production of 2-Methyl-4-((Trimethylsilyl)Ethynyl)Thiazole adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by modern analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.