Description

Methyl 2-Bromo-5-Fluoro-3-Nitrobenzoate is a high-purity, multi-functional aromatic ester building block critical for advanced organic synthesis. This compound is engineered to provide a reliable and reactive scaffold for constructing complex molecules in research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated and nitrated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its reactive bromo and nitro groups.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Biology & Proteomics: Employed as a building block for creating molecular probes, tags, and linkers for studying biological systems.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments due to its nitro and halogen substituents.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.

Basic Information

Item	Details
Product Name	Methyl 2-Bromo-5-Fluoro-3-Nitrobenzoate
CAS No.	328547-12-2
Molecular Formula	C8H5BrFNO4
Molecular Weight	278.03 g/mol
Synonyms	2-Bromo-5-fluoro-3-nitrobenzoic acid methyl ester; Methyl 2-bromo-5-fluoro-3-nitrobenzoate; Benzoic acid, 2-bromo-5-fluoro-3-nitro-, methyl ester; Methyl ester of 2-bromo-5-fluoro-3-nitrobenzoic acid; 328547-12-2; 2-Bromo-5-fluoro-3-nitro methyl benzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-5-Fluoro-3-Nitrobenzoate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets high-purity requirements for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.