Description

5-Azaspiro[2.4]Heptan-4-One,7-Amino-,(7R)-(9Ci) is a high-purity, chiral spirocyclic amine derivative, a crucial advanced pharmaceutical intermediate (API) for synthesizing complex bioactive molecules. Its unique constrained spirocyclic structure and stereochemistry make it a valuable building block for medicinal chemistry research and the development of novel therapeutics. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective synthesis to introduce complex molecular architectures.
• Bioconjugation & Probe Development: The primary amine functionality allows for conjugation, enabling the creation of biochemical probes and targeted drug delivery systems.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of high-value specialty chemicals and complex organic molecules.

Basic Information

Product Name	5-Azaspiro[2.4]Heptan-4-One,7-Amino-,(7R)-(9Ci)
CAS No.	328405-11-4
Molecular Formula	C6H10N2O
Molecular Weight	126.16 g/mol
Synonyms	(7R)-7-Amino-5-azaspiro[2.4]heptan-4-one; (7R)-7-Amino-5-azaspiro[2.4]heptan-4-one (9CI); 5-Azaspiro[2.4]heptan-4-one, 7-amino-, (7R)-; (7R)-7-Amino-5-azaspiro[2.4]heptane-4-one; 328405-11-4; (R)-7-Amino-5-azaspiro[2.4]heptan-4-one; 7-Amino-5-azaspiro[2.4]heptan-4-one, (R)-
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.4]Heptan-4-One,7-Amino-,(7R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.