Description

3-(Cyclopentylmethyl)-2-(Prop-2-Yn-1-Ylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is a sophisticated spirocyclic quinazolinone derivative, a key advanced intermediate in modern pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a crucial scaffold for synthesizing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the discovery and optimization of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile core scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Used in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs) during pre-clinical and clinical development phases.
• Chemical Biology Probes: Employed in the development of molecular probes to study specific biological pathways and protein functions.
• High-Value Fine Chemical Synthesis: Integral to the multi-step synthesis of complex, high-purity specialty chemicals for advanced applications.

Basic Information

Product Name	3-(Cyclopentylmethyl)-2-(Prop-2-Yn-1-Ylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One
CAS No.	328070-14-0
Molecular Formula	C26H30N2OS
Molecular Weight	418.60 g/mol
Synonyms	3-(Cyclopentylmethyl)-2-(prop-2-yn-1-ylsulfanyl)-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; 3H-Spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one, 3-(cyclopentylmethyl)-2-(2-propyn-1-ylthio)-; 2-(Prop-2-yn-1-ylsulfanyl)-3-(cyclopentylmethyl)-3H-spiro[benzo[h]quinazoline-5,1'-cyclopentan]-4(6H)-one; CAS 328070-14-0; Spirocyclic Quinazolinone Derivative; Advanced Pharmaceutical Intermediate
EINECS	Contact for details

Quality Control

Our 3-(Cyclopentylmethyl)-2-(Prop-2-Yn-1-Ylsulfanyl)-3H-Spiro[Benzo[H]Quinazoline-5,1'-Cyclopentan]-4(6H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.