Description

2-Chloro-5-Methyl-4-(Trifluoromethyl)Pyridine is a high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and chloro substituents make it an essential intermediate for creating molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the agrochemical and pharmaceutical industries for the synthesis of novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) and inflammatory diseases.
• Material Science Research: Employed in the creation of specialty chemicals, liquid crystals, and advanced polymers that require specific halogenated pyridine cores.
• Chemical Synthesis: Serves as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce diverse functional groups.

Basic Information

Product Name	2-Chloro-5-Methyl-4-(Trifluoromethyl)Pyridine
CAS No.	326894-70-6
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	4-(Trifluoromethyl)-2-chloro-5-methylpyridine; 2-Chloro-4-(trifluoromethyl)-5-methylpyridine; 5-Methyl-2-chloro-4-(trifluoromethyl)pyridine; 2-Chloro-5-methyl-4-trifluoromethylpyridine; 326894-70-6; 2-Chloro-5-methyl-4-(trifluoromethyl)pyridin; Pyridine, 2-chloro-5-methyl-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methyl-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, and NMR to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.