Description

[1,1'-Biphenyl]-3-Carbonitrile, 3'-(Bromomethyl)- is a high-purity, functionalized biphenyl derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive bromomethyl and nitrile groups for further functionalization.
• Ligand and Catalyst Development: Serves as a foundational structure for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as hole-transport materials or monomers for conjugated polymers.
• Cross-Coupling Reactions: The bromomethyl group makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	[1,1'-Biphenyl]-3-Carbonitrile, 3'-(Bromomethyl)-
CAS No.	325457-63-4
Molecular Formula	C14H10BrN
Molecular Weight	272.14 g/mol
Synonyms	3'-(Bromomethyl)-[1,1'-biphenyl]-3-carbonitrile; 3-(Bromomethyl)-3'-cyanobiphenyl; 3'-Bromomethylbiphenyl-3-carbonitrile; 3-Cyano-3'-bromomethylbiphenyl; Biphenyl-3-carbonitrile, 3'-(bromomethyl)-; (3'-Bromomethyl-biphenyl-3-yl)-acetonitrile (incorrect but common); 3-Bromomethyl-3'-cyanobiphenyl
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-3-Carbonitrile, 3'-(Bromomethyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for your synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.