Description

3-[(4-Chlorophenyl)Methyl]-Pyridine-4-Carboxylic Acid is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its unique molecular scaffold, which combines a pyridine-carboxylic acid moiety with a chlorobenzyl group, making it a critical building block for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed coupling reactions and other catalytic processes in fine chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and metal-organic frameworks (MOFs) due to its functional groups capable of coordination and conjugation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Product Name	3-[(4-Chlorophenyl)Methyl]-Pyridine-4-Carboxylic Acid
CAS No.	325162-36-5
Molecular Formula	C13H10ClNO2
Molecular Weight	247.68 g/mol
Synonyms	4-Pyridinecarboxylic acid, 3-[(4-chlorophenyl)methyl]-; 3-(4-Chlorobenzyl)isonicotinic Acid; 3-[(4-Chlorophenyl)methyl]pyridine-4-carboxylic acid; 3-(p-Chlorobenzyl)isonicotinic Acid; 3-(4-Chlorobenzyl)-4-pyridinecarboxylic Acid; 4-Carboxy-3-(4-chlorobenzyl)pyridine; Isonicotinic acid, 3-(4-chlorobenzyl)-
EINECS	Contact for details

Quality Control

Our production of 3-[(4-Chlorophenyl)Methyl]-Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.