Description

2,2,2-Trichloroethyl 2-Bromo-2-(3,4-Dimethoxyphenyl)Acetate is a specialized synthetic intermediate featuring a reactive bromoacetate ester group protected by a trichloroethyl moiety. This compound matters for its role as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, especially those with complex phenylacetic acid-derived structures.
• Peptide Mimetics & PROTAC Synthesis: Serves as a versatile building block for constructing peptide analogs and Proteolysis Targeting Chimeras (PROTACs) due to its reactive handles for further functionalization.
• Agrochemical Research: Used in the development of novel herbicides and plant growth regulators that leverage its dimethoxyphenyl pharmacophore.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Acts as a starting material for synthesizing activity-based probes and other tools for studying enzyme function and biological pathways.
• Polymer & Material Science: Can be utilized to introduce functional aromatic esters into polymer backbones or as a monomer for specialty polymers.

Basic Information

Product Name	2,2,2-Trichloroethyl 2-Bromo-2-(3,4-Dimethoxyphenyl)Acetate
CAS No.	322765-94-6
Molecular Formula	C₁₂H₁₂BrCl₃O₄
Molecular Weight	406.48 g/mol
Synonyms	2-Bromo-2-(3,4-dimethoxyphenyl)acetic acid 2,2,2-trichloroethyl ester; (3,4-Dimethoxyphenyl)(bromo)acetic acid trichloroethyl ester; α-Bromo-3,4-dimethoxyphenylacetic acid trichloroethyl ester; Trichloroethyl α-bromo-3,4-dimethoxyphenylacetate; 2,2,2-Trichloroethyl α-bromo-3,4-dimethoxybenzeneacetate; Troc-protected bromo veratric acid ester
EINECS	Contact for details

Quality Control

Our 2,2,2-Trichloroethyl 2-Bromo-2-(3,4-Dimethoxyphenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your research and development needs with reliable, high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.