Description

Dispiro[2.0.2.1]Heptane-1-Methanol, 7,7-Difluoro-, (1R,3R)-Rel- (9Ci) is a high-purity, chiral organic building block characterized by its unique spirocyclic and difluorinated structure. This compound is of significant value in advanced organic synthesis, particularly for introducing rigid, fluorinated motifs that can dramatically alter the physicochemical properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the design of novel pesticides and herbicides, where the difluoro and spirocyclic groups can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, where its rigid structure can influence material properties like thermal stability and optical activity.
• Asymmetric Catalysis Ligand Precursor: The chiral backbone can be functionalized to create novel ligands for asymmetric synthesis, improving enantioselectivity in catalytic reactions.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on understanding the effects of strategic fluorine incorporation in organic frameworks.

Basic Information

Item	Detail
Product Name	Dispiro[2.0.2.1]Heptane-1-Methanol, 7,7-Difluoro-, (1R,3R)-Rel- (9Ci)
CAS No.	321857-06-1
Molecular Formula	C8H10F2O
Molecular Weight	160.16 g/mol
Synonyms	(1R,3R)-rel-7,7-Difluorodispiro[2.0.2.1]heptane-1-methanol; rel-(1R,3R)-7,7-Difluorodispiro[2.0.2.1]heptane-1-methanol; 7,7-Difluorodispiro[2.0.2.1]heptane-1-methanol, (1R,3R)-rel-; Difluorinated Spirocyclic Methanol Derivative; Chiral Difluoro Building Block
EINECS	Contact for details

Quality Control

Every batch of Dispiro[2.0.2.1]Heptane-1-Methanol, 7,7-Difluoro-, (1R,3R)-Rel- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to ensure exceptional chemical and enantiomeric purity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.