Description

Spiro[1,3-Dioxolane-2,2-[6]Oxabicyclo[3.1.0]Hexane], (+)- is a high-purity, chiral spirocyclic compound of significant interest in advanced organic synthesis. Its unique, rigid three-dimensional structure makes it a valuable building block and chiral auxiliary for the development of complex molecules with specific stereochemistry. This compound is primarily sought by pharmaceutical R&D and fine chemical sectors for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Acts as a chiral auxiliary or ligand to induce stereoselectivity in catalytic reactions, enabling the production of enantiomerically pure compounds.
• Advanced Material Research: Used in the development of specialty polymers and liquid crystals where a rigid, defined molecular geometry is required.
• Agrochemical Synthesis: Employed in the research and development of new, more selective pesticides and herbicides.
• Academic & Industrial R&D: A valuable tool for chemists exploring new reaction methodologies and constructing complex molecular architectures.

Basic Information

Item	Details
Product Name	Spiro[1,3-Dioxolane-2,2-[6]Oxabicyclo[3.1.0]Hexane], (+)-
CAS No.	319491-92-4
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(+)-Spiro[1,3-dioxolane-2,2'-[6]oxabicyclo[3.1.0]hexane]; (1S,5S,6R)-6,8-Dioxatricyclo[3.2.1.02,4]octane, 3,7-dioxa-; (+)-6,8-Dioxatricyclo[3.2.1.02,4]octane-3,7-dione ethylene acetal; (1S,5S,6R)-3,7-Dioxa-6,8-dioxatricyclo[3.2.1.02,4]octane; Chiral Spiroketal; (+)-Spiroketal Auxiliary
EINECS	Contact for details

Quality Control

Our production of Spiro[1,3-Dioxolane-2,2-[6]Oxabicyclo[3.1.0]Hexane], (+)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical purity, and identity. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation, making this material suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.