Description

2-((1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1H-Pyrazol-5-Yl)Methylene)Malononitrile is a high-value, functionalized heterocyclic compound that serves as a critical synthetic intermediate. Its molecular architecture, featuring a pyridine core substituted with chloro and trifluoromethyl groups linked to a pyrazole-malononitrile moiety, makes it a versatile building block for advanced material and life science applications. This compound is primarily sought by R&D and process development teams in the agrochemical and pharmaceutical sectors for creating novel active ingredients with enhanced properties.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel insecticides and herbicides, leveraging the pyridine and pyrazole pharmacophores for bioactivity.
• Pharmaceutical Research: Used as a sophisticated scaffold in medicinal chemistry for developing potential drug candidates targeting various diseases.
• Material Science: Serves as a building block for organic electronic materials, such as non-fullerene acceptors in organic photovoltaics (OPVs) due to its electron-withdrawing malononitrile group.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create fluorescent or bioactive probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Item	Details
Product Name	2-((1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1H-Pyrazol-5-Yl)Methylene)Malononitrile
CAS No.	318248-55-4
Molecular Formula	C14H5ClF3N5
Molecular Weight	359.67 g/mol
Synonyms	2-[(1-{3-Chloro-5-(trifluoromethyl)pyridin-2-yl}-1H-pyrazol-5-yl)methylene]propanedinitrile; (Z)-2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile; 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-5-yl)methylene)malononitrile; 3-Chloro-5-(trifluoromethyl)-2-[5-[(Z)-2,2-dicyanovinyl]-1H-pyrazol-1-yl]pyridine; CAS 318248-55-4
EINECS	Contact for details

Quality Control

Our production of 2-((1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1H-Pyrazol-5-Yl)Methylene)Malononitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure consistency and reliability for your critical R&D and scale-up processes. Certificates of Analysis (COA) with detailed chromatographic data are provided as standard, guaranteeing full traceability and compliance with your internal quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.