Description

Diethyl 3-([3-(Trifluoromethyl)Anilino]Carbonyl)-1,2-Cyclopropanedicarboxylate is a high-value, multifunctional chemical intermediate characterized by its cyclopropane core and trifluoromethyl aniline moiety. This compound is engineered to serve as a critical building block in advanced organic synthesis, offering unique reactivity for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and chemical resistance properties.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a component in the synthesis of electron-transport or host materials for advanced display technologies.
• Ligand and Catalyst Development: The structure provides a versatile scaffold for creating novel chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and protein interactions within biological systems.

Basic Information

Product Name	Diethyl 3-([3-(Trifluoromethyl)Anilino]Carbonyl)-1,2-Cyclopropanedicarboxylate
CAS No.	318237-96-6
Molecular Formula	C₁₈H₂₀F₃NO₅
Molecular Weight	387.35 g/mol
Synonyms	Diethyl 3-[(3-(trifluoromethyl)phenyl)carbamoyl]cyclopropane-1,2-dicarboxylate; 1,2-Cyclopropanedicarboxylic acid, 3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]-, 1,2-diethyl ester; 3-(3-Trifluoromethylphenylcarbamoyl)cyclopropane-1,2-dicarboxylic acid diethyl ester; Ethyl 3-([3-(trifluoromethyl)anilino]carbonyl)cyclopropane-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Every batch of Diethyl 3-([3-(Trifluoromethyl)Anilino]Carbonyl)-1,2-Cyclopropanedicarboxylate is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with the stringent purity requirements demanded for pharmaceutical and agrochemical research. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.