Description

Spiro-[n-(4-Nitrophenyl)Piperidine-4',1-(1,2,3,4-Tetrahydro-β-Carboline)]Hydrochloride is a high-purity, complex heterocyclic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate spirocyclic and tetrahydro-β-carboline structure makes it a valuable scaffold for medicinal chemists exploring novel therapeutic agents. This compound is primarily utilized by R&D laboratories and pharmaceutical companies focused on developing new drugs targeting central nervous system disorders and other complex diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study receptor interactions and enzyme inhibition.
• Academic Research: Employed in university and institutional labs for synthetic methodology development and exploring new chemical space in organic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and process development.

Basic Information

Item	Detail
Product Name	Spiro-[n-(4-Nitrophenyl)Piperidine-4',1-(1,2,3,4-Tetrahydro-β-Carboline)]Hydrochloride
CAS No.	317822-52-9
Molecular Formula	C22H22N4O2·HCl
Molecular Weight	410.90 g/mol
Synonyms	1',2',3',4'-Tetrahydrospiro[piperidine-4,1'-pyrido[3,4-b]indole] Hydrochloride; 4-(4-Nitrophenyl)-1,2,3,4-tetrahydrospiro[pyrido[3,4-b]indole-1,4'-piperidine] Hydrochloride; Spiro(1,2,3,4-tetrahydro-β-carboline-1,4'-piperidine) Hydrochloride derivative; 317822-52-9; (4-Nitrophenyl)-Spiro-Tetrahydro-β-Carboline-Piperidine HCl
EINECS	Contact for details

Quality Control

Our Spiro-[n-(4-Nitrophenyl)Piperidine-4',1-(1,2,3,4-Tetrahydro-β-Carboline)]Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.